Description

(4R)-4,4A,5,6,7,7A,8,8Aβ-Octahydro-4,4Aβ,7β,7Aβ-Tetramethyl-5α,8α-Epoxy-2H-Indeno[5,6-B]Furan-2-One CAS NO 73020-89-0 is a high-purity, complex sesquiterpene lactone derivative with a defined stereochemistry. This compound serves as a critical advanced intermediate in the synthesis of biologically active molecules and fine chemicals. It is primarily sought by pharmaceutical R&D and specialty chemical manufacturers for developing novel therapeutic agents and high-value synthetic targets.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in anti-inflammatory and anticancer research.
• Organic Synthesis: Used in advanced organic chemistry for constructing complex polycyclic frameworks due to its rigid, functionalized structure.
• Natural Product Analog Synthesis: Serves as a precursor for synthesizing analogs of sesquiterpene-based natural products for biological evaluation.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in studies of stereoselective chemical transformations.
• Flavor & Fragrance Industry: Potential use in the synthesis of high-value, complex aroma chemicals with unique olfactory properties.
• Agrochemical Research: Investigated as an intermediate for developing new plant protection agents with novel modes of action.
• Academic & Industrial R&D: A valuable compound for chemical libraries and research programs focused on medicinal chemistry and chemical biology.

Basic Information

Product Name	(4R)-4,4A,5,6,7,7A,8,8Aβ-Octahydro-4,4Aβ,7β,7Aβ-Tetramethyl-5α,8α-Epoxy-2H-Indeno[5,6-B]Furan-2-One
CAS No.	73020-89-0
Molecular Formula	C17H24O3
Molecular Weight	276.37 g/mol
Synonyms	4R-4,4a,5,6,7,7a,8,8aβ-Octahydro-4,4aβ,7β,7aβ-tetramethyl-5α,8α-epoxy-2H-indeno[5,6-b]furan-2-one; (4R)-4,4a,5,6,7,7a,8,8aβ-Octahydro-4,4aβ,7β,7aβ-tetramethyl-5α,8α-epoxy-2H-indeno[5,6-b]furan-2-one; 2H-Indeno[5,6-b]furan-2-one, 4,4a,5,6,7,7a,8,8aβ-octahydro-4,4aβ,7β,7aβ-tetramethyl-5α,8α-epoxy-, (4R)-; Sesquiterpene lactone derivative; Indenofuranone derivative; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (4R)-4,4A,5,6,7,7A,8,8Aβ-Octahydro-4,4Aβ,7β,7Aβ-Tetramethyl-5α,8α-Epoxy-2H-Indeno[5,6-B]Furan-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and isomeric purity suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.