Description

Methyl 4-[(Propionyl)Phenylamino]Piperidine-4-Carboxylate is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex pharmacologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and pain management research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel piperidine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Process Chemistry Development: Used in the optimization and scale-up of synthetic routes for target compounds in pre-clinical and clinical development.
• Reference Standard: Employed as an analytical standard for quality control and method validation in API manufacturing.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and advanced intermediates.

Basic Information

Product Name	Methyl 4-[(Propionyl)Phenylamino]Piperidine-4-Carboxylate
CAS No.	72996-78-2
Molecular Formula	C17H24N2O3
Molecular Weight	304.39 g/mol
Synonyms	Methyl 4-(N-phenylpropionamido)piperidine-4-carboxylate; 4-[(Propionyl)phenylamino]piperidine-4-carboxylic acid methyl ester; 4-(Propionylamino)-4-carbomethoxypiperidine; 4-(N-Phenylpropionamido)isonipecotic acid methyl ester; Methyl 4-(propionylamino)-4-piperidinecarboxylate; 72996-78-2; Methyl 4-(propionylphenylamino)piperidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4-[(Propionyl)Phenylamino]Piperidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.