Description

Benzydamine n-Oxide Hydrogen Maleate is a high-purity pharmaceutical intermediate and active metabolite of the anti-inflammatory agent benzydamine. This compound is critical for research and development in the synthesis of novel therapeutic agents and for analytical reference standards. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories engaged in drug metabolism studies, impurity profiling, and quality control. The material is supplied under stringent quality protocols to ensure consistency and reliability for demanding industrial and research applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis and development of benzydamine-based anti-inflammatory and analgesic drugs.
• Reference Standard: Certified reference material (CRM) for analytical method development, validation, and quality control testing in pharmaceutical laboratories.
• Metabolite Studies: Used in pharmacokinetic and drug metabolism research to study the biotransformation pathways of benzydamine.
• Impurity Profiling: Essential for identifying and quantifying related substances and degradation products in active pharmaceutical ingredient (API) batches.
• Preclinical Research: Employed in biological and pharmacological studies to investigate the efficacy and mechanisms of action of benzydamine derivatives.
• Chemical Synthesis: Serves as a specialized reagent for organic synthesis and process chemistry in fine chemical production.

Basic Information

Product Name	Benzydamine n-Oxide Hydrogen Maleate
CAS No.	72962-60-8
Molecular Formula	C19H23N3O6
Molecular Weight	389.41 g/mol
Synonyms	Benzydamine N-Oxide Hydrogen Maleate; Benzydamine N-Oxide Maleate; 1-Benzyl-3-(3-dimethylaminopropoxy)-1H-indazole N-Oxide Maleate; Benzydamine Impurity F (Maleate); Benzydamine Related Compound F; Benzydamine Metabolite (N-Oxide) Maleate Salt; 1H-Indazole, 1-benzyl-3-[3-(dimethylamino)propoxy]-, 5-oxide, (2Z)-2-butenedioate (1:1)
EINECS	Contact for details

Quality Control

Our Benzydamine n-Oxide Hydrogen Maleate is manufactured and tested under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC and other chromatographic techniques, to ensure it meets high-purity standards suitable for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, purity, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.