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1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-L-Serine, Sodium Salt CAS NO 72904-02-0
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CAS No.:72904-02-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-L-Serine, Sodium Salt is a high-purity, synthetic phospholipid derivative, specifically a phosphatidylserine (PS) species. This compound is a critical functional component in the formulation of advanced lipid-based delivery systems and biomimetic membranes. It is essential for research and manufacturing in the pharmaceutical, biotechnology, and nutraceutical industries, where precise lipid composition is paramount for efficacy and stability.
Application
- Liposome & Nanoparticle Formulation: A key excipient for creating stable, targeted drug delivery vehicles for cancer therapeutics, vaccines, and gene therapy.
- Biomimetic Membrane Research: Used to construct model cell membranes (e.g., supported lipid bilayers) for studying protein-lipid interactions, membrane permeability, and cellular signaling pathways.
- Pharmaceutical Actives: Serves as an active pharmaceutical ingredient (API) or critical intermediate in cognitive health and neurological disorder treatments, leveraging the role of phosphatidylserine in neuronal function.
- Diagnostic Reagent Component: Incorporated into assay kits and diagnostic tools where specific lipid environments are required for accurate biomarker detection.
- Cell Culture & Regenerative Medicine: Enhances cell culture media supplements and scaffolds to improve cell viability, differentiation, and tissue engineering outcomes.
- Cosmeceutical Formulations: Used in high-end skincare products for its purported role in supporting skin barrier function and cellular repair mechanisms.
Basic Information
| Product Name | 1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-L-Serine, Sodium Salt |
| CAS No. | 72904-02-0 |
| Molecular Formula | C38H73NNaO10P |
| Molecular Weight | 757.96 g/mol |
| Synonyms | DPPS, Sodium Salt; 1,2-Dihexadecanoyl-sn-glycero-3-phospho-L-serine sodium salt; L-α-Phosphatidylserine, dipalmitoyl, sodium salt; Phosphatidylserine (16:0/16:0) sodium salt; PS(16:0/16:0) Na; 3-sn-Phosphatidyl-L-serine, dipalmitoyl, sodium salt; DPPS-Na; 1,2-Dipalmitoylphosphatidylserine |
| EINECS | Contact for details |
Quality Control
Our 1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-L-Serine, Sodium Salt is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, and stringent limits for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) compliant with cGMP guidelines for pharmaceutical applications.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Under these conditions, the product is typically stable for at least 24 months. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% (Area Percent) |
| Water Content (KF) | ≤ 2.0 % |
| Residual Solvents (GC) | Meets ICH Q3C guidelines |
| Heavy Metals | ≤ 20 ppm |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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