Description

2,5-Piperazinedione,3,6-Diethyl-,cis-(9Ci) is a specialized heterocyclic diketopiperazine derivative with a defined cis-configuration. This compound serves as a valuable high-purity building block and key intermediate in advanced organic synthesis, where its structural features enable precise molecular construction. It is primarily required by R&D and production teams in the pharmaceutical and fine chemical industries for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of novel drug candidates, particularly in medicinal chemistry research targeting bioactive molecules.
• Peptidomimetic Research: Used as a constrained dipeptide mimic (diketopiperazine) to study structure-activity relationships and improve metabolic stability in peptide-based therapeutics.
• Ligand and Catalyst Development: Acts as a precursor or ligand in asymmetric synthesis and catalysis due to its chiral centers and chelating potential.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and the discovery of new chemical entities with biological activity.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex, high-value specialty chemicals requiring specific stereochemistry.
• Material Science Precursor: Investigated as a monomer or building block for novel polymers and functional organic materials.

Basic Information

Product Name	2,5-Piperazinedione,3,6-Diethyl-,cis-(9Ci)
CAS No.	72882-83-8
Molecular Formula	C8H14N2O2
Molecular Weight	170.21 g/mol
Synonyms	cis-3,6-Diethyl-2,5-piperazinedione; cis-3,6-Diethylpiperazine-2,5-dione; 3,6-Diethyl-2,5-piperazinedione, cis-; 2,5-Diketopiperazine, 3,6-diethyl-, cis-; cis-3,6-Diethylpiperazine-2,5-diketone; (3R,6R)-3,6-Diethylpiperazine-2,5-dione; (3S,6S)-3,6-Diethylpiperazine-2,5-dione
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione,3,6-Diethyl-,cis-(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay, enantiomeric purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.