Description

3,6-Dichloro-5-Methylpyrazine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key precursor for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is critically needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for developing new active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its pyrazine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of functional organic materials and coordination polymers due to its carboxylic acid and halogen functionalities.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3,6-Dichloro-5-Methylpyrazine-2-Carboxylic Acid
CAS No.	72876-12-1
Molecular Formula	C7H4Cl2N2O2
Molecular Weight	219.03 g/mol
Synonyms	5-Methyl-3,6-dichloropyrazine-2-carboxylic acid; 3,6-Dichloro-5-methyl-2-pyrazinecarboxylic acid; 2-Pyrazinecarboxylic acid, 3,6-dichloro-5-methyl-; 3,6-Dichloro-5-methylpyrazinecarboxylic acid; 3,6-Dichloro-5-methyl-2-carboxypyrazine
EINECS	Contact for details

Quality Control

Our 3,6-Dichloro-5-Methylpyrazine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.