Description

(±)-Erythro-(S*,S*)-1-[2,3-(Dihydro-7-Methyl-1H-Inden-4-Yl)Oxy]-3-[(1-Methylethyl)Amino]-2-Butanolhydrochloride is a high-purity, synthetically derived chiral compound of significant interest in advanced pharmaceutical research and development. This substance serves as a critical intermediate or reference standard for the synthesis and study of novel active pharmaceutical ingredients (APIs), particularly those targeting adrenergic pathways. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in the development of cardiovascular and respiratory therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex β-adrenergic blocking agents (β-blockers).
• Reference Standard: Used for analytical method development, validation, and quality control (QC) in pharmaceutical laboratories.
• Biochemical Research: Tool compound for studying adrenergic receptor (AR) interactions, selectivity, and signaling mechanisms.
• Process Chemistry: Serves as a starting material or intermediate in scale-up and process optimization for API manufacturing under GMP conditions.
• Metabolite Studies: Utilized in the identification and synthesis of drug metabolites for pharmacokinetic and safety profiling.

Basic Information

Product Name	(±)-Erythro-(S*,S*)-1-[2,3-(Dihydro-7-Methyl-1H-Inden-4-Yl)Oxy]-3-[(1-Methylethyl)Amino]-2-Butanolhydrochloride
CAS No.	72795-01-8
Molecular Formula	C17H26ClNO2
Molecular Weight	311.85 g/mol
Synonyms	1-(7-Methyl-2,3-dihydro-1H-inden-4-yloxy)-3-(isopropylamino)butan-2-ol hydrochloride; (±)-Erythro-1-(7-Methylindanyloxy)-3-isopropylaminobutan-2-ol HCl; 4-[1-Hydroxy-2-(isopropylamino)butoxy]-7-methylindane hydrochloride; Indenolol Hydrochloride (Erythro racemate); ICI 89406; (±)-Erythro-Indenolol HCl; 1-(Indan-4-yloxy)-3-(isopropylamino)-2-butanol hydrochloride (7-methyl derivative)
EINECS	Contact for details

Quality Control

Our (±)-Erythro-(S*,S*)-1-[2,3-(Dihydro-7-Methyl-1H-Inden-4-Yl)Oxy]-3-[(1-Methylethyl)Amino]-2-Butanolhydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere if specified and opened in a low-humidity environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	Erythro diastereomer ≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.