Description

(R)-(+)-1-Amino-2-(Methoxymethyl)Pyrrolidine CAS NO 72748-99-3 is a high-purity chiral pyrrolidine derivative, serving as a critical building block in asymmetric synthesis. Its value lies in its role as a versatile chiral ligand and organocatalyst, enabling the production of enantiomerically pure pharmaceutical intermediates. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients with high stereoselectivity.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, such as hydrogenation and cross-coupling.
• As an organocatalyst for enantioselective synthesis in pharmaceutical research and development.
• Key intermediate in the synthesis of complex, biologically active molecules and active pharmaceutical ingredients (APIs).
• Building block for the preparation of novel catalysts and ligands with tailored properties.
• Used in academic and industrial research for methodological development in organic chemistry.
• Potential application in the synthesis of agrochemicals requiring specific stereochemistry.

Basic Information

Product Name	(R)-(+)-1-Amino-2-(Methoxymethyl)Pyrrolidine
CAS No.	72748-99-3
Molecular Formula	C7H16N2O
Molecular Weight	144.21 g/mol
Synonyms	(R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine; (R)-1-Amino-2-(methoxymethyl)pyrrolidine; (R)-2-(Methoxymethyl)pyrrolidin-1-amine; (R)-AMP; (R)-1-Amino-2-methoxymethylpyrrolidine; (R)-1-AMP; (R)-Proline-derived amine; (R)-2-Methoxymethyl-1-aminopyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-Amino-2-(Methoxymethyl)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.