Description

1-Methylpiperidin-3-One Hydrobromide is a high-purity organic salt with the CAS registry number 72285-75-7, serving as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile intermediate for constructing complex nitrogen-containing heterocycles, which are foundational to numerous active pharmaceutical ingredients and specialty chemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality synthetic precursors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing piperidine or related N-heterocyclic scaffolds for neurological and therapeutic agents.
• Agrochemical Synthesis: Used in the development and production of advanced crop protection agents and herbicides, where its structural motif contributes to biological activity.
• Fine Chemical Manufacturing: Employed as a specialized building block for creating complex molecules used in dyes, pigments, and functional materials.
• Research & Development: A valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Chemical Synthesis: Facilitates various organic transformations, including alkylation and condensation reactions, to introduce the 1-methylpiperidin-3-one moiety into target molecules.

Basic Information

Product Name	1-Methylpiperidin-3-One Hydrobromide
CAS No.	72285-75-7
Molecular Formula	C6H12NO•BrH or C6H13BrNO
Molecular Weight	195.08 g/mol (approx.)
Synonyms	1-Methyl-3-piperidone hydrobromide; 1-Methylpiperidin-3-one HBr; 3-Piperidone, 1-methyl-, hydrobromide; 1-Methyl-3-piperidone HBr; N-Methyl-3-piperidone hydrobromide; 1-Methyl-3-oxopiperidinium bromide; 72285-75-7; N-Methyl-3-piperidone HBr
EINECS	Contact for details

Quality Control

Our 1-Methylpiperidin-3-One Hydrobromide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practices (cGMP) where applicable, and the material is suitable for use in GMP-regulated synthesis. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to meeting the stringent requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.