Description

(S)-2-Methylbutanoic Acid [(1Ar,3Aα,5Aα,8Aα,9As)-Decahydro-1Aβ,4α,8β-Trimethyl-7-Oxo-3H-Oxireno[3,3A]Azuleno[6,5-B]Furan-3α-Yl] Ester is a high-purity, complex organic ester with a defined stereochemistry. This compound is valued for its role as a key chiral intermediate and building block in advanced synthetic chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex drug candidates, particularly in stereoselective reactions.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Production: Serves as a specialized intermediate in the manufacture of flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial Research: Employed in chemical research for methodological studies in asymmetric synthesis and natural product chemistry.
• Process Chemistry Development: Used for scaling up synthetic routes in pilot plants and optimizing production processes for complex molecules.

Basic Information

Product Name	(S)-2-Methylbutanoic Acid [(1Ar,3Aα,5Aα,8Aα,9As)-Decahydro-1Aβ,4α,8β-Trimethyl-7-Oxo-3H-Oxireno[3,3A]Azuleno[6,5-B]Furan-3α-Yl] Ester
CAS No.	72264-71-2
Molecular Formula	C₂₀H₃₀O₅
Molecular Weight	350.45 g/mol
Synonyms	(S)-2-Methylbutyric Acid Artemisinin Ester; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl (2S)-2-methylbutanoate; Arteannuin B derivative; Qinghaosu derivative; (S)-2-Methylbutanoic acid, ester with artemisinin; Artemisinin (S)-2-methylbutyrate
EINECS	Contact for details

Quality Control

Our (S)-2-Methylbutanoic Acid Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.