Description

5-Hydroxy-6,8,11,14-Eicosatetraenoic Acid is a specialized eicosanoid derivative, a key intermediate in the biosynthesis of bioactive lipid mediators. This compound matters for researchers and developers focused on inflammatory pathways, cellular signaling, and metabolic studies. It is primarily needed by the pharmaceutical, biotechnology, and advanced life science research sectors for drug discovery and biochemical analysis.

Application

• Biochemical Research: Used as a reference standard and precursor in the study of lipoxygenase and cytochrome P450 pathways.
• Pharmaceutical Development: Serves as a critical intermediate for synthesizing novel anti-inflammatory and pro-resolving lipid mediators.
• Cell Signaling Studies: Applied in vitro to investigate the role of hydroxyeicosatetraenoic acids (HETEs) in cellular communication and immune response.
• Metabolite Analysis: Utilized as an analytical standard in LC-MS and GC-MS methods for profiling eicosanoids in biological samples.
• Enzyme Activity Assays: Acts as a substrate or product in assays for lipoxygenase and other related enzymes.

Basic Information

Product Name	5-Hydroxy-6,8,11,14-Eicosatetraenoic Acid
CAS No.	72255-35-7
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	5-HETE; 5-Hydroxyeicosatetraenoic Acid; (6E,8Z,11Z,14Z)-5-Hydroxyicosa-6,8,11,14-tetraenoic Acid; 5(S)-HETE; 5-Hydroxy-6,8,11,14-eicosatetraenoic Acid; 5-Lipoxygenase metabolite of arachidonic acid
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-6,8,11,14-Eicosatetraenoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere such as argon or nitrogen, as the compound is easily oxidized. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or film
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.