Description

2α-Hydroxyeupatolide 8-o-Angelate is a specialized sesquiterpene lactone derivative, a compound of significant interest in advanced chemical synthesis and research. Its value lies in its unique molecular structure, which serves as a critical intermediate or reference standard for developing novel bioactive compounds. This product is essential for pharmaceutical R&D laboratories, agrochemical innovators, and academic institutions focused on natural product chemistry and medicinal plant research. Its specific stereochemistry and functional groups make it a valuable building block for probing structure-activity relationships.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or a reference standard in the synthesis and study of new therapeutic agents, particularly those targeting inflammation or cancer.
• Natural Product Chemistry: Serves as a pure, characterized compound for the isolation, identification, and structural elucidation of related sesquiterpene lactones from plant extracts.
• Biochemical Research: Employed in enzymatic studies and assays to investigate biological pathways and mechanisms of action due to its specific bioactive scaffold.
• Agrochemical Innovation: Acts as a lead compound or synthetic precursor in the development of new plant protection agents with novel modes of action.
• Academic & Analytical Laboratories: Utilized as a high-purity analytical standard for method development, calibration, and quality control in chromatographic analyses (HPLC, LC-MS).
• Fine Chemical Synthesis: Provides a complex, chiral starting material for the total synthesis of other natural products or for derivatization studies in organic chemistry.

Basic Information

Item	Details
Product Name	2α-Hydroxyeupatolide 8-o-Angelate
CAS No.	72229-39-1
Molecular Formula	C20H24O7
Molecular Weight	376.40 g/mol
Synonyms	2α-Hydroxyeupatolide 8-O-angelate; 8-O-Angeloyl-2α-hydroxyeupatolide; 2α-Hydroxy-8-O-angeloyleupatolide; Eupatolide 8-O-angelate derivative; [1aR-(1aα,4aα,7α,7aβ,7bα)]-1a,2,3,4,4a,5,7,7a,7b,8,9,9a-Dodecahydro-7b-hydroxy-4a,7-dimethyl-1-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9a-yl 2-methylbut-2-enoate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 2α-Hydroxyeupatolide 8-o-Angelate is subjected to rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identification (IR, NMR), and other critical parameters is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.