Description

Vitamin D2 Tosylate is a key chemical intermediate, specifically a tosylate ester derivative of ergocalciferol (Vitamin D2). This compound is of significant value in pharmaceutical research and development for its role in the synthesis of more complex, biologically active Vitamin D analogs. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas like oncology, dermatology, and metabolic bone disease research.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel Vitamin D receptor (VDR) modulators and prodrugs.
• Research & Development: Used in academic and industrial laboratories for studying Vitamin D metabolism and creating new chemical entities for biological screening.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) related to Vitamin D.

Basic Information

Product Name	Vitamin D2 Tosylate
CAS No.	72204-99-0
Molecular Formula	C35H52O4S
Molecular Weight	568.86 g/mol
Synonyms	Ergocalciferol Tosylate; Vitamin D2 p-Toluenesulfonate; (3β,5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol 3-(4-methylbenzenesulfonate); 9,10-Secoergosta-5,7,10(19),22-tetraen-3β-ol 3-(p-toluenesulfonate); Ergocalciferol 3-tosylate; D2 Tosylate; Tocris-2892 (Research Code)
EINECS	Contact for details

Quality Control

Our Vitamin D2 Tosylate is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. The material is light-sensitive and should be handled under subdued lighting conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.