Description

Calcitetrol is a high-purity, synthetic vitamin D3 metabolite of significant pharmaceutical and research interest. Its precise chemical structure makes it a critical intermediate and reference standard in the development of treatments for metabolic bone disorders and related endocrine conditions. This compound is essential for manufacturers and research institutions focused on endocrinology, nephrology, and advanced pharmaceutical synthesis.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the manufacture of active pharmaceutical ingredients (APIs) for treating conditions like hypocalcemia, secondary hyperparathyroidism, and osteoporosis.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related pharmaceutical products and nutritional supplements.
• Biochemical Research: Employed in life science research to study vitamin D metabolism, calcium homeostasis, and cell differentiation pathways.
• Clinical Diagnostics: Serves as a calibrant or standard in the development of immunoassays and chromatographic methods for measuring vitamin D metabolites in biological samples.

Basic Information

Product Name	Calcitetrol
CAS No.	72203-93-1
Molecular Formula	C₂₇H₄₄O₃
Molecular Weight	416.64 g/mol
Synonyms	1α,25-Dihydroxyvitamin D3; 1α,25-Dihydroxycholecalciferol; 1,25-Dihydroxyvitamin D3; 1,25(OH)₂D₃; Calcitriol Impurity C; Rocaltrol Impurity; (5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1α,3β,25-triol
EINECS	Contact for details

Quality Control

Our Calcitetrol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label. Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.