Description

1A,3,5A,8,8A,9,10,10A-Octahydro-4,10A-Dimethyl-8-Methyleneoxireno[5,6]Cyclodeca[1,2-B]Furan-7(2H)-One is a high-purity, complex sesquiterpene lactone derivative with significant synthetic utility. This compound serves as a critical advanced intermediate or building block for the research and development of novel bioactive molecules. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for its unique structural framework.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to construct intricate natural product analogs or new chemical entities.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and compound identification.
• Biochemical Research: Investigated for its potential biological activity and interaction with specific enzymes or cellular pathways.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high structural precision.

Basic Information

Item	Detail
Product Name	1A,3,5A,8,8A,9,10,10A-Octahydro-4,10A-Dimethyl-8-Methyleneoxireno[5,6]Cyclodeca[1,2-B]Furan-7(2H)-One
CAS No.	72203-21-5
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	8-Methylene-4,10a-dimethyl-1a,3,5a,8,8a,9,10,10a-octahydrooxireno[5,6]cyclodeca[1,2-b]furan-7(2H)-one; Parthenolide analog; Parthenolide derivative; Germacranolide sesquiterpene lactone; Oxireno[5,6]cyclodeca[1,2-b]furan-7(2H)-one derivative
EINECS	Contact for details

Quality Control

Our 1A,3,5A,8,8A,9,10,10A-Octahydro-4,10A-Dimethyl-8-Methyleneoxireno[5,6]Cyclodeca[1,2-B]Furan-7(2H)-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and potential for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.