Description

(E)-1,4,5,6-Tetrahydro-2-[2-(3-Hydroxyphenyl)Vinyl]-1-Methylpyrimidine-1,3-Diylium [R-(R*,R*)]-Tartrate is a high-purity, chiral organic salt with significant pharmaceutical relevance. This compound is valued for its role as a key synthetic intermediate or active pharmaceutical ingredient (API) in advanced research and development. It is primarily sought by pharmaceutical manufacturers and research institutions engaged in the synthesis of novel therapeutic agents, particularly those targeting neurological or cardiovascular pathways.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex drug molecules and APIs.
• Neurological Research: Used in the development and study of compounds targeting neurotransmitter systems.
• Cardiovascular Drug Development: Serves as a precursor in the synthesis of potential vasoactive or cardioprotective agents.
• Chiral Synthesis: Provides a source of stereochemical complexity for the production of enantiomerically pure pharmaceuticals.
• Biochemical Research: Employed as a tool compound in pharmacological assays and receptor binding studies.
• Process Chemistry & Scale-up: Used in optimizing synthetic routes from laboratory to pilot and commercial scale.

Basic Information

Item	Detail
Product Name	(E)-1,4,5,6-Tetrahydro-2-[2-(3-Hydroxyphenyl)Vinyl]-1-Methylpyrimidine-1,3-Diylium [R-(R*,R*)]-Tartrate
CAS No.	71865-30-0
Molecular Formula	C₁₉H₂₄N₂O₇
Molecular Weight	392.40 g/mol
Synonyms	Rivastigmine Related Compound; (E)-Rivastigmine Tartrate; (E)-1,4,5,6-Tetrahydro-2-[2-(3-hydroxyphenyl)ethenyl]-1-methylpyrimidinium (R,R)-tartrate; (E)-SDZ ENA 713 Tartrate; (E)-Exelon Related Compound; (E)-1-Methyl-2-[(E)-2-(3-hydroxyphenyl)vinyl]-1,4,5,6-tetrahydropyrimidinium (2R,3R)-2,3-dihydroxybutanedioate; (E)-1,4,5,6-Tetrahydro-2-[(E)-2-(3-hydroxyphenyl)vinyl]-1-methylpyrimidinium (2R,3R)-tartrate
EINECS	Contact for details

Quality Control

Our (E)-1,4,5,6-Tetrahydro-2-[2-(3-Hydroxyphenyl)Vinyl]-1-Methylpyrimidine-1,3-Diylium [R-(R*,R*)]-Tartrate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profiling, to ensure compliance with pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and related substances are provided to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.