Description

Fuc-Alpha1,2Gal-Beta1,3Galnac-Beta1,4(Neu5Ac-Alpha2,3)Gal-Beta1,4Glc-Beta1,1 Ceramide, Nh4, Bovine is a complex, well-defined glycosphingolipid (GSL) derived from bovine brain tissue, specifically a sialylated and fucosylated ganglioside. This high-purity reference standard is critical for advancing research in glycobiology, immunology, and neuroscience by providing a structurally precise model compound. It is essential for scientists in pharmaceutical R&D, diagnostic development, and academic research who require reliable, high-quality biomolecules to study cell signaling, receptor interactions, and biomarker discovery.

Application

• Biomedical Research: Used as a critical reference standard and antigen in studies of ganglioside function, cell adhesion, and signal transduction pathways.
• Immunology & Vaccine Development: Serves as a target antigen for investigating antibody responses and developing diagnostic assays or therapeutic vaccines targeting specific glycolipid epitopes.
• Neuroscience Research: Employed in studying the role of complex gangliosides in neural development, synaptic plasticity, and neurodegenerative diseases.
• Diagnostic Reagent Production: Acts as a key component in the manufacturing of calibration standards and controls for clinical diagnostic kits detecting anti-ganglioside antibodies.
• Glycobiology Tool: Essential for enzymatic studies, glycan array fabrication, and as a substrate or inhibitor in assays probing glycosyltransferase or glycosidase activity.
• Quality Control & Standardization: Provides a benchmark for purity and identity in the quality control of related biological products and research materials.

Basic Information

Product Name	Fuc-Alpha1,2Gal-Beta1,3Galnac-Beta1,4(Neu5Ac-Alpha2,3)Gal-Beta1,4Glc-Beta1,1 Ceramide, Nh4, Bovine
CAS No.	71812-11-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bovine Brain Ganglioside (specific isomer); IV3Neu5Ac,II3Fuc-nLc4Ceramide (ammonium salt); Sialyl Lewis x ganglioside (sLex); Fucosyl-GM1 (structural analog); CD15s antigen; SSEA-1 (Sialylated form); Hematoside derivative; Glycosphingolipid GSL-1b
EINECS	Contact for details

Quality Control

This high-purity biochemical is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Quality is verified using advanced techniques including HPLC, mass spectrometry (MS), and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in Chloroform/Methanol/Water mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.