Description

10-Hydroxy-11,12-Epoxyeicosa-5,8,14-Trienoic Acid is a specialized eicosanoid derivative, a key intermediate in the study of fatty acid metabolism and signaling pathways. This compound matters for its role as a precursor in the biosynthesis of bioactive lipid mediators, which are critical for understanding inflammatory and regulatory processes. It is primarily needed by researchers and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery, biochemical research, and the development of analytical standards.

Application

• Biochemical Research: Used as a critical reference standard and intermediate in the study of lipoxygenase and cytochrome P450 metabolic pathways.
• Pharmaceutical Development: Serves as a key building block or metabolite analog in the discovery of novel anti-inflammatory and cardiovascular drugs.
• Analytical Chemistry: Employed as a high-purity calibrant in LC-MS, HPLC, and GC-MS methods for the quantification of eicosanoids in biological samples.
• Cell Signaling Studies: Applied in vitro to investigate the role of epoxy-hydroxy fatty acids in cellular communication and receptor interactions.
• Academic Research: Utilized in universities and research institutes for fundamental studies on lipid biochemistry and oxidative stress.
• Diagnostic Reagent Manufacturing: Incorporated into the development of ELISA kits and other diagnostic assays targeting specific lipid mediators.

Basic Information

Product Name	10-Hydroxy-11,12-Epoxyeicosa-5,8,14-Trienoic Acid
CAS No.	71799-95-6
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	10-Hydroxy-11,12-epoxy-5,8,14-eicosatrienoic acid; 10-HETE-11,12-epoxide; 10-Hydroxy-11,12-epoxy-5Z,8Z,14Z-eicosatrienoic acid; 10-Hydroxy-11(12)-epoxy-5,8,14-eicosatrienoic acid; 10-H-11,12-EE-5,8,14-ETrE; 10-H-11,12-EpETrE; 10-Hydroxy-11,12-epoxyeicosatrienoic acid; HEETA
EINECS	Contact for details

Quality Control

Our 10-Hydroxy-11,12-Epoxyeicosa-5,8,14-Trienoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.