Description

5(S)-Hpete is a specialized, biologically active eicosanoid derivative and a key intermediate in the lipoxygenase pathway. This compound is of significant interest for its role as a precursor to various leukotrienes and other lipid mediators involved in inflammatory and immune responses. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for biochemical research, drug discovery, and the development of analytical standards.

Application

• Biochemical Research: Used as a critical substrate and reference standard in studies of the lipoxygenase and leukotriene biosynthesis pathways.
• Pharmaceutical Development: Serves as a key intermediate in the research and synthesis of novel anti-inflammatory and immunomodulatory drug candidates.
• Cell Signaling Studies: Employed to investigate the role of hydroxyeicosatetraenoic acids (HETEs) and related eicosanoids in cellular communication and disease mechanisms.
• Analytical Standard: Essential for the calibration of analytical equipment (HPLC, LC-MS) and for quality control in the production of related bioactive lipids.
• Enzyme Activity Assays: Acts as a specific substrate for assessing the activity of 5-lipoxygenase and other related enzymes in vitro.

Basic Information

Product Name	5(S)-Hpete
CAS No.	71774-08-8
Molecular Formula	C20H32O4
Molecular Weight	336.47 g/mol
Synonyms	5(S)-HPETE; (5S)-Hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic Acid; 5(S)-Hydroperoxyeicosatetraenoic Acid; 5-HPETE; 5(S)-Hpete; 5-Lipoxygenase metabolite; Leukotriene A4 precursor
EINECS	Contact for details

Quality Control

Our 5(S)-Hpete is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability data. We adhere to relevant industry standards for fine chemicals and bioactive lipids.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or film
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (UV)	≥ 90%
Solvent	Ethanol or other suitable solvent (specified per lot)
Peroxide Value	Monitored per lot

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.