Description

Fenoprofen Calcium Salt, Dihydrate is the calcium salt form of the non-steroidal anti-inflammatory drug (NSAID) fenoprofen. This compound is a key active pharmaceutical ingredient (API) and intermediate valued for its enhanced stability and solubility profile compared to the free acid. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of analgesic and anti-inflammatory formulations.

Application

• Pharmaceutical API: Primary use as the active ingredient in solid oral dosage forms (e.g., tablets, capsules) for pain and inflammation management.
• Analgesic Formulations: Manufacture of prescription medications for conditions such as arthritis, mild to moderate pain, and musculoskeletal disorders.
• Chemical Synthesis Intermediate: Serves as a critical intermediate in the synthesis of other fenoprofen-based derivatives or prodrugs.
• Reference Standard: Used in analytical laboratories as a high-purity standard for quality control (QC) and research & development (R&D) method development.
• Preclinical & Clinical Research: Employed in pharmacological studies to investigate NSAID mechanisms, efficacy, and safety profiles.

Basic Information

Product Name	Fenoprofen Calcium Salt, Dihydrate
CAS No.	71720-56-4
Molecular Formula	C30H26CaO6 · 2H2O
Molecular Weight	558.61 g/mol (Anhydrous: 522.61)
Synonyms	Fenoprofen Calcium; Fenoprofen Calcium Dihydrate; (±)-Fenoprofen Calcium Salt Dihydrate; DL-Fenoprofen Calcium Salt Dihydrate; 2-(3-Phenoxyphenyl)propionic Acid Calcium Salt Dihydrate; Nalfon® (brand name equivalent); Calcium 2-(3-phenoxyphenyl)propionate dihydrate
EINECS	Contact for details

Quality Control

Our Fenoprofen Calcium Salt, Dihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (Calcium)	Positive
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	5.0% - 7.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	Contact for details
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.