Description

5,6-Dihydroxy-7,9,11,14-Eicosatetraenoic Acid is a specialized eicosanoid derivative, a key intermediate in the biosynthesis of bioactive lipid mediators. This compound matters for its role in advanced biochemical research and pharmaceutical development, particularly in studying inflammation and cell signaling pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing novel therapeutics and analytical standards.

Application

• Biochemical Research: Used as a critical reference standard and intermediate in the study of lipoxygenase and cytochrome P450 metabolic pathways.
• Pharmaceutical Development: Serves as a key building block for the synthesis of novel anti-inflammatory agents and other bioactive lipid analogs.
• Cell Signaling Studies: Employed in vitro and in vivo to investigate the role of specific eicosanoids in cellular communication and immune response.
• Analytical Chemistry: Functions as a high-purity calibrant and internal standard in advanced chromatographic (HPLC, LC-MS) methods for lipidomics.
• Enzyme Substrate: Acts as a substrate for specific enzymes like leukotriene synthases in enzymatic assays and inhibitor screening.
• Fine Chemical Synthesis: A valuable chiral synthon for the custom synthesis of complex, biologically active molecules.

Basic Information

Product Name	5,6-Dihydroxy-7,9,11,14-Eicosatetraenoic Acid
CAS No.	71651-85-9
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	5,6-DiHETE; (5S,6S)-Dihydroxy-(7E,9E,11Z,14Z)-eicosatetraenoic Acid; 5,6-Dihydroxy-7,9,11,14-eicosatetraenoic acid; 5,6-DiHETrE; 5,6-Dihydroxyeicosatetraenoic Acid; Leukotriene analog intermediate; 5,6-DiHETE acid
EINECS	Contact for details

Quality Control

Our 5,6-Dihydroxy-7,9,11,14-Eicosatetraenoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.