Description

Cyclohexanecarboxylic Acid, 2-(Chlorocarbonyl)-, Methyl Ester, trans- (9Ci) is a high-purity, functionalized cyclohexane derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the precise stereochemistry and reactive carbonyl chloride and ester functionalities, enabling the controlled construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific stereochemical configurations.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where the trans- configuration is critical for the desired property.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for producing specialty polymers with tailored thermal or mechanical properties.
• Academic and R&D: A valuable reagent for methodological research in organic chemistry, particularly in studies involving stereoselective reactions and ring systems.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 2-(Chlorocarbonyl)-, Methyl Ester, trans- (9Ci)
CAS No.	71606-03-6
Molecular Formula	C9H13ClO3
Molecular Weight	204.65 g/mol
Synonyms	trans-2-(Chlorocarbonyl)cyclohexanecarboxylic acid methyl ester; Methyl trans-2-(chloroformyl)cyclohexanecarboxylate; trans-2-Carbomethoxycyclohexanecarbonyl chloride; (1R,2R)-2-(Methoxycarbonyl)cyclohexanecarbonyl chloride (enantiomer); (1S,2S)-2-(Methoxycarbonyl)cyclohexanecarbonyl chloride (enantiomer); Cyclohexanecarbonyl chloride, 2-(methoxycarbonyl)-, trans-; 2-(Chlorocarbonyl)cyclohexanecarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 2-(Chlorocarbonyl)-, Methyl Ester, trans- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent hydrolysis of the acid chloride functionality. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% trans- isomer
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.