Description

(1R)-2,3,4,5,7,8-Hexahydro-1α,4α-Dimethyl-7-Isopropylideneazulen-6(1H)-One is a high-purity, specialized sesquiterpenoid derivative with a defined stereochemistry. This compound is valued for its unique azulene-based structure, which serves as a critical advanced intermediate in the synthesis of complex organic molecules. It is primarily sought by pharmaceutical R&D and fine chemical sectors for developing novel active ingredients and fragrances.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in anti-inflammatory and antiviral research.
• Fragrance & Flavor Synthesis: Used in the creation of complex, high-value aroma chemicals due to its unique azulene-derived scent profile.
• Organic Synthesis Research: Serves as a versatile starting material or intermediate in academic and industrial laboratories for methodological studies and natural product synthesis.
• Agrochemical Development: Potential intermediate in the research and development of new, targeted crop protection agents.
• Material Science: Investigated as a precursor for specialty polymers or organic electronic materials with specific optical properties.

Basic Information

Product Name	(1R)-2,3,4,5,7,8-Hexahydro-1α,4α-Dimethyl-7-Isopropylideneazulen-6(1H)-One
CAS No.	71305-96-9
Molecular Formula	C₁₅H₂₂O
Molecular Weight	218.33 g/mol
Synonyms	(1R)-7-Isopropylidene-1α,4α-dimethyl-2,3,4,5,7,8-hexahydro-6(1H)-azulenone; (1R)-1α,4α-Dimethyl-7-(propan-2-ylidene)octahydroazulen-6-one; (-)-Isocomene; (1R)-Isocomene; 1R-Isocomene; Azulen-6(1H)-one derivative; Sesquiterpenoid ketone
EINECS	Contact for details

Quality Control

Every batch of (1R)-2,3,4,5,7,8-Hexahydro-1α,4α-Dimethyl-7-Isopropylideneazulen-6(1H)-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and isomeric purity suitable for research and development applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.