Description

(4S)-8β-Ethoxy-4,4Aβ,5,6,7,7Aβ,8,9-Octahydro-4β-Hydroxy-6,6,8-Trimethylazuleno[5,6-C]Furan-3(1H)-One is a high-purity, complex sesquiterpene lactone derivative with a defined stereochemistry. This compound is valued for its role as a critical synthetic intermediate and building block in advanced organic synthesis, particularly for the development of novel pharmacologically active molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the discovery of new therapeutic agents and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, especially in anti-inflammatory and anticancer research.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to construct intricate molecular frameworks found in natural products and specialty chemicals.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new bioactive compounds within the sesquiterpene class.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and compound identification.
• Fine Chemical Production: Acts as a starting material for the manufacture of high-value, low-volume specialty chemicals with specific stereochemical requirements.

Basic Information

Product Name	(4S)-8β-Ethoxy-4,4Aβ,5,6,7,7Aβ,8,9-Octahydro-4β-Hydroxy-6,6,8-Trimethylazuleno[5,6-C]Furan-3(1H)-One
CAS No.	71305-66-3
Molecular Formula	C₁₈H₂₆O₄
Molecular Weight	306.40 g/mol
Synonyms	8β-Ethoxy-4β-hydroxy-6,6,8-trimethyl-1,4,4a,5,6,7,7a,8,9,9a-decahydroazuleno[5,6-c]furan-3(1H)-one; (4S,4aS,7aS,9aR)-8β-Ethoxy-4β-hydroxy-6,6,8-trimethyl-1,4,4a,5,6,7,7a,8,9,9a-decahydroazuleno[5,6-c]furan-3(1H)-one; Ethoxyhydroxydimethyloctahydroazulenofuranone; A sesquiterpene lactone derivative. Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (4S)-8β-Ethoxy-4,4Aβ,5,6,7,7Aβ,8,9-Octahydro-4β-Hydroxy-6,6,8-Trimethylazuleno[5,6-C]Furan-3(1H)-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure consistent identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing specific results for assay, related substances, and chiral purity are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.