Description

(4S)-8β-Ethoxy-4,4Aβ,5,6,7,7Aβ,8,9-Octahydro-4β-Hydroxy-6,6,8-Trimethylazuleno[5,6-C]Furan-1(3H)-One is a high-purity, complex sesquiterpene lactone derivative with a defined stereochemistry. This compound matters as a sophisticated chemical intermediate and research standard, valued for its unique azulene-fused furanone structure. It is primarily needed by R&D and process development teams in the pharmaceutical and fine chemical industries for synthesis and analytical purposes.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Organic Synthesis Research: Advanced starting material for exploring new chemical reactions and constructing complex molecular architectures in academic and industrial labs.
• Reference Standard: High-purity standard for analytical method development, validation, and quality control in chromatographic analysis (HPLC, GC).
• Medicinal Chemistry: Core scaffold for structure-activity relationship (SAR) studies and drug discovery programs targeting specific biological pathways.
• Fine Chemical Production: Precursor in the multi-step synthesis of specialty chemicals, flavors, and fragrances.
• Process Chemistry Development: Used to optimize and scale up synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.

Basic Information

Product Name	(4S)-8β-Ethoxy-4,4Aβ,5,6,7,7Aβ,8,9-Octahydro-4β-Hydroxy-6,6,8-Trimethylazuleno[5,6-C]Furan-1(3H)-One
CAS No.	71305-65-2
Molecular Formula	C₁₈H₂₆O₄
Molecular Weight	306.40 g/mol
Synonyms	8β-Ethoxy-4,4aβ,5,6,7,7aβ,8,9-octahydro-4β-hydroxy-6,6,8-trimethylazuleno[5,6-c]furan-1(3H)-one; (4S)-8β-Ethoxy-4,4aβ,5,6,7,7aβ,8,9-octahydro-4β-hydroxy-6,6,8-trimethylazuleno[5,6-c]furan-1(3H)-one; Azuleno[5,6-c]furan-1(3H)-one derivative; Sesquiterpene lactone ethoxy derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (4S)-8β-Ethoxy-4,4Aβ,5,6,7,7Aβ,8,9-Octahydro-4β-Hydroxy-6,6,8-Trimethylazuleno[5,6-C]Furan-1(3H)-One is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets precise customer specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.