Description

2-Bromo-4-Chlorobutanoyl Chloride is a versatile bifunctional acid chloride intermediate, crucial for introducing both bromine and chlorine functional groups in a single synthetic step. Its high reactivity makes it a valuable building block for constructing complex molecular architectures in advanced chemical synthesis. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated butyric acid derivatives.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the 2-bromo-4-chloro moiety is integral to biological activity.
• Organic Synthesis Reagent: Serves as a versatile electrophile in nucleophilic acyl substitution reactions for attaching the butanoyl chain to amines, alcohols, or other nucleophiles.
• Ligand and Catalyst Preparation: Employed in the modification of complex molecules to create novel ligands or organocatalysts for asymmetric synthesis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with specific halogenated side chains.
• Chemical Research: Utilized in academic and industrial R&D for exploring new reaction pathways and developing novel heterocyclic compounds.

Basic Information

Item	Detail
Product Name	2-Bromo-4-Chlorobutanoyl Chloride
CAS No.	71254-32-5
Molecular Formula	C4H5BrCl2O
Molecular Weight	219.89 g/mol
Synonyms	4-Chloro-2-bromobutanoyl chloride; 2-Bromo-4-chlorobutyryl chloride; Butanoyl chloride, 2-bromo-4-chloro-; α-Bromo-γ-chlorobutyryl chloride; γ-Chloro-α-bromobutyryl chloride; 2-Bromo-4-chlorobutanoic acid chloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chlorobutanoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and assay. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.