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1,2-Ditridecanoyl-Sn-Glycero-3-Phosphocholine CAS NO 71242-28-9


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CAS No.:71242-28-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Ditridecanoyl-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a phosphatidylcholine with defined C13:0 acyl chains. This compound is a critical building block for creating stable, well-defined lipid bilayers and vesicles for advanced research and formulation development. It is essential for scientists and manufacturers in the life sciences, pharmaceutical, and biotechnology sectors who require precise control over membrane composition and properties.

Application

  • Liposome & Nanoparticle Formulation: A key component for constructing unilamellar vesicles (LUVs, SUVs) and solid lipid nanoparticles (SLNs) with tailored membrane fluidity and stability.
  • Drug Delivery Systems: Used to create biocompatible carriers for targeted and sustained release of active pharmaceutical ingredients (APIs), enhancing therapeutic efficacy.
  • Membrane Biophysics Research: Serves as a standard or model membrane lipid for studying protein-lipid interactions, membrane permeability, and fusion mechanisms.
  • Biomimetic Coatings & Sensors: Employed in the development of supported lipid bilayers (SLBs) for biosensor platforms and surface functionalization.
  • Cell Culture & Transfection Reagents: A component in specialized media supplements and non-viral transfection agents to improve cell membrane health and gene delivery.
  • Cosmetic & Dermal Formulations: Incorporated into high-end cosmetic products as a skin-identical lipid to restore barrier function and improve active ingredient penetration.

Basic Information

Product Name 1,2-Ditridecanoyl-Sn-Glycero-3-Phosphocholine
CAS No. 71242-28-9
Molecular Formula C34H68NO8P
Molecular Weight 649.88 g/mol
Synonyms PC(13:0/13:0); 1,2-Ditridecanoylphosphatidylcholine; 1,2-Di-C13:0-PC; DTPC; 1,2-Dimyristoylphosphatidylcholine (C13:0 isomer); 1,2-Ditridecanoyl-sn-glycerol-3-phosphocholine; 3-sn-Phosphatidylcholine, 1,2-ditridecanoyl-; Tridecanoyl Phosphatidylcholine
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Quality Control

Our 1,2-Ditridecanoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the stringent requirements for research and GMP-grade applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (NMR) Conforms to structure
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 98.0%
Solubility Soluble in chloroform, methanol, ethanol; forms liposomes in aqueous buffers
Residual Solvents (GC) Meets ICH guidelines
Heavy Metals < 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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