Description

15(S)-Hete Solution is a high-purity, standardized solution of the bioactive lipid mediator 15(S)-Hydroxyeicosatetraenoic acid. This compound serves as a critical reference standard and research tool in biochemical and pharmacological studies. It is essential for scientists and quality control laboratories in the pharmaceutical, biotechnology, and academic research sectors requiring precise and reliable analytical standards.

Application

• Biochemical Research Standard: Used as a primary reference material for the quantification and identification of eicosanoids in complex biological samples via LC-MS, HPLC, or ELISA.
• Cell Signaling Studies: Employed in research to investigate the role of 15(S)-HETE in inflammatory pathways, angiogenesis, and cellular proliferation mechanisms.
• Pharmaceutical Development: Serves as a key analytical standard in the development and validation of assays for drug candidates targeting lipoxygenase (LOX) pathways.
• Diagnostic Kit Manufacturing: Utilized as a calibrator or control in the production of immunoassay kits designed to detect eicosanoid levels in clinical or research settings.
• Metabolomics and Lipidomics: An essential component in lipid profiling studies to understand disease states related to lipid metabolism dysregulation.
• Enzyme Activity Assays: Acts as a substrate or product in enzymatic assays for lipoxygenases and other related enzymes.

Basic Information

Product Name	15(S)-Hete Solution
CAS No.	71030-36-9
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	15(S)-HETE; (15S)-15-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid; 15S-Hydroxyeicosatetraenoic Acid; 15(S)-HETE Solution; 15S-HETE; 15-HETE, (15S)-; 15(S)-Hydroxy-5,8,11,13-eicosatetraenoic Acid
EINECS	Contact for details

Quality Control

Every batch of our 15(S)-Hete Solution is manufactured and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) that detail purity, concentration, and solvent specifications, ensuring traceability and compliance with research-grade standards. Our quality commitment supports reliable and reproducible results for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the solution to equilibrate to room temperature before opening to minimize moisture condensation. Keep away from heat and ignition sources.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95% (15(S)-HETE)
Concentration	Typically 1.0 mg/mL in ethanol or specified solvent
Stereochemical Purity	≥ 98% 15(S) isomer
Solvent Content (GC)	As specified on COA
Water Content (Karl Fischer)	< 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.