Description

(+/-)12-Hpete CAS NO 71030-35-8 is a high-purity eicosanoid derivative, specifically a 12-hydroxyeicosatetraenoic acid ethyl ester, valued for its role as a key biochemical intermediate in lipid signaling research. This compound is essential for studying the arachidonic acid cascade and its physiological effects. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors.

Application

• Biochemical Research: Critical standard and intermediate for studying lipoxygenase pathways, inflammation, and cell signaling mechanisms.
• Pharmaceutical Development: Used as a reference compound and building block in the R&D of novel anti-inflammatory and metabolic disorder therapeutics.
• In Vitro Diagnostics: Serves as a calibrant or component in assay kits for eicosanoid profiling and metabolic studies.
• Academic Research: A fundamental tool in university and institutional labs for cardiovascular, neurological, and immunological research projects.
• Chemical Synthesis: Acts as a versatile chiral synthon for the preparation of more complex bioactive lipid analogs and probes.

Basic Information

Product Name	(+/-)12-Hpete
CAS No.	71030-35-8
Molecular Formula	C22H36O3
Molecular Weight	348.52 g/mol
Synonyms	12-Hpete ethyl ester; 12(S)-Hpete ethyl ester; 12-Hydroperoxyeicosatetraenoic acid ethyl ester; (±)-12-Hpete; 12(S)-HPETE EE; 12-Hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid ethyl ester; 12(S)-Hydroperoxyeicosatetraenoic acid ethyl ester; 12-LOX metabolite ethyl ester
EINECS	Contact for details

Quality Control

Our (+/-)12-Hpete is produced under strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and stability, meeting the stringent requirements for research-grade biochemicals. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (by NMR/IR), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to oxidation and light. For long-term storage, solutions should be prepared in anhydrous, oxygen-free solvents and kept at -80°C. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 90% (by weight)
Solubility	Soluble in ethanol, DMSO, chloroform

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.