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(1R,8Aβ)-Decahydro-2α-(1-Hydroxy-1-Methylethyl)-4Aα-Methyl-8-Methylene-1β,7β-Naphthalenediol CAS NO 70902-38-4


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CAS No.:70902-38-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(1R,8Aβ)-Decahydro-2α-(1-Hydroxy-1-Methylethyl)-4Aα-Methyl-8-Methylene-1β,7β-Naphthalenediol is a high-purity, stereochemically defined diterpenoid derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile chiral building block for complex organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel therapeutic agents and high-value specialty chemicals.

Application

  • Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly for anti-inflammatory or neurological applications.
  • Asymmetric Synthesis: Utilized as a sophisticated chiral pool reagent or scaffold for constructing complex, stereoselective molecules.
  • Natural Product Synthesis: Serves as a core structural unit for the total or semi-synthesis of complex diterpenoid natural products.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
  • Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
  • Biochemical Research: Investigated for potential biological activity and enzyme interaction studies.

Basic Information

Product Name (1R,8Aβ)-Decahydro-2α-(1-Hydroxy-1-Methylethyl)-4Aα-Methyl-8-Methylene-1β,7β-Naphthalenediol
CAS No. 70902-38-4
Molecular Formula C₁₅H₂₆O₃
Molecular Weight 254.37 g/mol
Synonyms 8-Methylene-4a-methyl-1,2,3,4,4a,5,6,7,8,8a-decahydro-2-(1-hydroxy-1-methylethyl)-1,7-naphthalenediol; (1R,2S,4aR,7S,8aS)-2-(2-Hydroxypropan-2-yl)-4a-methyl-8-methylenedecahydronaphthalene-1,7-diol; 8-Methylene-4a-methyl-1,2,3,4,4a,5,6,7,8,8a-decahydro-2-(1-hydroxy-1-methylethyl)naphthalene-1,7-diol; Diterpenoid Diol Derivative; Labdane Diol Derivative; Contact for additional synonyms.
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Quality Control

Our (1R,8Aβ)-Decahydro-2α-(1-Hydroxy-1-Methylethyl)-4Aα-Methyl-8-Methylene-1β,7β-Naphthalenediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; handle and store under an inert atmosphere if prolonged storage is required to maintain optimal purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 97.0%
Chiral Purity ≥ 98.0% de
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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