Description

Keto Diclofenac Sodium Salt is a key pharmaceutical intermediate and analytical reference standard. This compound is of significant commercial importance for the research and development of non-steroidal anti-inflammatory drugs (NSAIDs) and their metabolites. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories engaged in drug development, quality control, and metabolic studies.

Application

• Pharmaceutical Intermediate: Critical synthesis building block for novel NSAID derivatives and prodrug development.
• Analytical Reference Standard: Used for method development, validation, and quantification in HPLC, LC-MS, and GC-MS analyses for quality control and regulatory compliance.
• Metabolite Research: Serves as a reference compound for studying the metabolic pathways and pharmacokinetics of Diclofenac.
• Impurity Standard: Essential for identifying, characterizing, and controlling related substances and degradation products in Diclofenac sodium active pharmaceutical ingredient (API) and finished dosage forms.
• Biochemical Research: Used in in-vitro studies to investigate cyclooxygenase (COX) enzyme inhibition mechanisms and structure-activity relationships (SAR).

Basic Information

Product Name	Keto Diclofenac Sodium Salt
CAS No.	70757-34-5
Molecular Formula	C14H9Cl2NNaO3
Molecular Weight	333.12 g/mol
Synonyms	2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium salt; Sodium 2-[(2,6-dichlorophenyl)amino]phenylacetate; Diclofenac Sodium Impurity; Diclofenac Related Compound; 2-(2,6-Dichloroanilino)phenylacetic acid sodium salt; Ketodiclofenac Sodium; Keto-Diclofenac Na
EINECS	Contact for details

Quality Control

Our Keto Diclofenac Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates and reference standards. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.