Description

3-Hydroxy-1,3,5(10)-Estratrien-17-One 2,4-Dinitrophenyl Hydrazone is a high-purity chemical derivative, specifically a hydrazone derivative of a steroidal ketone, used as a critical reference standard and analytical reagent. This compound matters for its role in ensuring the accuracy and reliability of sophisticated analytical methods, particularly in pharmaceutical research and quality control laboratories. It is primarily needed by manufacturers and R&D facilities in the pharmaceutical, biotechnology, and analytical chemistry sectors for method development, validation, and impurity profiling.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of related steroid compounds or process impurities in active pharmaceutical ingredients (APIs).
• Analytical Chemistry Reagent: Serves as a derivatization agent or a calibration standard in chromatographic analyses such as High-Performance Liquid Chromatography (HPLC) and Thin-Layer Chromatography (TLC).
• Research & Development: Employed in academic and industrial research for studying steroid metabolism, synthesis pathways, and the development of new analytical methodologies.
• Quality Control & Assurance: Essential for in-house quality control protocols to verify the identity and purity of steroid-based products, ensuring batch-to-batch consistency.

Basic Information

Product Name	3-Hydroxy-1,3,5(10)-Estratrien-17-One 2,4-Dinitrophenyl Hydrazone
CAS No.	70636-63-4
Molecular Formula	C24H24N4O5
Molecular Weight	448.47 g/mol
Synonyms	Estrone 2,4-Dinitrophenylhydrazone; 17-Oxoestra-1,3,5(10)-trien-3-ol 2,4-Dinitrophenylhydrazone; Estrone DNP Hydrazone; 3-Hydroxyestra-1,3,5(10)-trien-17-one 2,4-dinitrophenylhydrazone; Estrone (2,4-DNPH); DNPH Derivative of Estrone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for parameters such as HPLC purity, melting point, and spectral identification are available upon request, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.