Description

1H-1,2,4-Triazole-1-Ethanol, .Beta.-(1,1-Biphenyl-4-Yloxy)-.Alpha.-(1,1-Dimethylethyl)-, (.Alpha.R,.Beta.S)-Rel- is a high-purity, stereochemically defined triazole derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the development of molecules with specific three-dimensional configurations critical for biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and development of novel active pharmaceutical ingredients (APIs), particularly for creating enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, especially in antifungal and other specialty drug candidates.
• Agrochemical Research: Used as a precursor in the synthesis of novel, high-efficacy pesticides and fungicides where the specific stereochemistry is crucial for target interaction.
• Asymmetric Synthesis: Employed in academic and industrial laboratories as a reagent or ligand to induce chirality in complex organic transformations.
• Material Science: Potential application in the synthesis of advanced organic materials, such as liquid crystals or polymers with specific optical properties.
• Chemical Biology: Utilized as a molecular probe or tag in biochemical research due to the reactivity of the triazole moiety.

Basic Information

Product Name	1H-1,2,4-Triazole-1-Ethanol, .Beta.-(1,1-Biphenyl-4-Yloxy)-.Alpha.-(1,1-Dimethylethyl)-, (.Alpha.R,.Beta.S)-Rel-
CAS No.	70585-36-3
Molecular Formula	C20H23N3O2
Molecular Weight	337.42 g/mol
Synonyms	rel-(αR,βS)-β-(4-Biphenylyloxy)-α-(tert-butyl)-1H-1,2,4-triazole-1-ethanol; (αR,βS)-β-(4-Phenylphenoxy)-α-(tert-butyl)-1H-1,2,4-triazole-1-ethanol; tert-Butyl(4-biphenylyloxy)methyl-1H-1,2,4-triazol-1-ylmethanol; 1-(1-Hydroxy-2-((1,1'-biphenyl)-4-yloxy)-3,3-dimethylbutyl)-1H-1,2,4-triazole; (rel)-(αR,βS)-β-(Biphenyl-4-yloxy)-α-tert-butyl-1H-1,2,4-triazole-1-ethanol; Biphenyl-tert-butyl-triazole ethanol derivative
EINECS	Contact for details

Quality Control

Our 1H-1,2,4-Triazole-1-Ethanol, .Beta.-(1,1-Biphenyl-4-Yloxy)-.Alpha.-(1,1-Dimethylethyl)-, (.Alpha.R,.Beta.S)-Rel- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.