Description

Territrem A CAS NO 70407-19-1 is a high-purity, naturally derived tremorgenic mycotoxin, specifically a member of the territrem family. This compound is of significant interest in biochemical and pharmacological research due to its potent and specific acetylcholinesterase (AChE) inhibitory activity. It serves as a critical reference standard and active research material for scientists and institutions focused on neurobiology, toxicology, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a potent and selective acetylcholinesterase (AChE) inhibitor in enzyme kinetics and inhibition studies.
• Pharmacological Studies: Serves as a key tool compound for investigating cholinergic pathways, neurotoxicity, and potential therapeutic targets for neurological disorders.
• Reference Standard: Essential for the qualitative and quantitative analysis (HPLC, LC-MS) of mycotoxins in analytical laboratories for food safety, environmental, and clinical toxicology.
• Neuroscience Research: Applied in cellular and animal models to study tremorgenic mechanisms and the physiological impact of AChE modulation.
• Drug Discovery: Acts as a lead compound or molecular probe in the screening and development of new acetylcholinesterase inhibitors.
• Toxicology & Safety Assessment: Utilized to understand the toxicological profile of tremorgenic mycotoxins and for risk assessment in contaminated commodities.

Basic Information

Product Name	Territrem A
CAS No.	70407-19-1
Molecular Formula	C23H28O7
Molecular Weight	416.47 g/mol
Synonyms	Territrem A; Territrem-A; Territrem A (mycotoxin); 3,4,4a,5,6,7,8,8a-Octahydro-4a,5,8a-trimethyl-2,8-dioxospiro[naphthalene-6(2H),2'-[2H]pyran]-3-carboxylic acid, 7-(acetyloxy)-4,4a,5,6,7,8,8a,8b-octahydro-3-hydroxy-4a,5,8a-trimethyl-2,8-dioxospiro[naphthalene-6(2H),2'-[2H]pyran]-3-carboxylic acid 7-acetate (non-preferred IUPAC); Tremorgenic mycotoxin A.
EINECS	Contact for details

Quality Control

Our Territrem A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity confirmation and structural verification via spectroscopic methods (NMR, MS). A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the material may be stored at 2-8°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. This product is intended for research use only in a laboratory setting.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with structure
Purity (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.