Description

1-(Chloroacetyl)-4-(3-Chlorophenyl)Piperazine Hydrochloride is a high-purity, synthetically versatile piperazine derivative used as a critical pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of complex molecules, particularly in medicinal chemistry and active pharmaceutical ingredient (API) development. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and fine chemical sectors seeking reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various bioactive molecules and potential drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of novel compounds with piperazine-based pharmacophores.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a building block in multi-step synthetic routes for the production of complex APIs.
• Agrochemical Research: Employed in the development of new pesticides and herbicides where the piperazine moiety contributes to biological activity.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized chemicals for various industrial applications.

Basic Information

Product Name	1-(Chloroacetyl)-4-(3-Chlorophenyl)Piperazine Hydrochloride
CAS No.	70395-06-1
Molecular Formula	C12H15Cl2N2O·HCl
Molecular Weight	307.62 g/mol
Synonyms	1-(2-Chloroacetyl)-4-(3-chlorophenyl)piperazine hydrochloride; 4-(3-Chlorophenyl)-1-(chloroacetyl)piperazine hydrochloride; N-(3-Chlorophenyl)-N'-(chloroacetyl)piperazine hydrochloride; 3-Chloro-N-(2-chloroacetyl)-N-phenylpiperazine hydrochloride; 1-Chloroacetyl-4-(3-chlorophenyl)piperazine HCl; m-Chlorophenylpiperazine chloroacetamide hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Chloroacetyl)-4-(3-Chlorophenyl)Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets exacting standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.