Description

(1R,2S,4Aα)-Decahydro-2,5,5,8Aβ-Tetramethyl-1β-[(E)-3-Methylpenta-2,4-Dienyl]-2α,3β-Naphthalenediol CAS NO 70387-36-9 is a complex, high-purity diterpenoid diol derivative with a specific stereochemistry. This compound is valued for its role as a key chiral intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and bioactive molecules. It is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, process development, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, especially in steroid-like or terpenoid-based therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its complex polycyclic framework.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric transformations to create enantiomerically pure compounds.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical fidelity.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• Academic Research: A valuable compound for studies in organic synthesis methodology and natural product chemistry.

Basic Information

Product Name	(1R,2S,4Aα)-Decahydro-2,5,5,8Aβ-Tetramethyl-1β-[(E)-3-Methylpenta-2,4-Dienyl]-2α,3β-Naphthalenediol
CAS No.	70387-36-9
Molecular Formula	C20H34O2
Molecular Weight	306.49 g/mol
Synonyms	1,2,3,4,4a,5,6,7,8,8a-Decahydro-2,5,5,8a-tetramethyl-1-[(2E)-3-methyl-2,4-pentadien-1-yl]-2,3-naphthalenediol; (1R,2S,4aR,8aS)-1-[(E)-3-Methylpenta-2,4-dienyl]decahydro-2,5,5,8a-tetramethyl-2,3-naphthalenediol; 2,3-Naphthalenediol, 1,2,3,4,4a,5,6,7,8,8a-decahydro-2,5,5,8a-tetramethyl-1-[(2E)-3-methyl-2,4-pentadien-1-yl]-, (1R,2S,4aR,8aS)-; Diterpenoid Diol Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports the needs of research and cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.