Description

3-(p-Chlorophenyl)-1-[(4-Hydroxy-4-Phenylpiperidino)Acetyl]Urea is a specialized organic compound with a complex molecular structure, serving as a key intermediate in advanced pharmaceutical synthesis. This compound matters for its role in the development of targeted active pharmaceutical ingredients (APIs), where precise chemical architecture is critical for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical and life sciences industries focused on creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapies.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for complex, high-value APIs.
• Biochemical Research: Employed in biochemical assays and as a tool compound for investigating specific biological pathways and enzyme interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	3-(p-Chlorophenyl)-1-[(4-Hydroxy-4-Phenylpiperidino)Acetyl]Urea
CAS No.	70166-95-9
Molecular Formula	C20H22ClN3O3
Molecular Weight	387.86 g/mol
Synonyms	1-[(4-Hydroxy-4-phenyl-1-piperidinyl)acetyl]-3-(4-chlorophenyl)urea; 3-(4-Chlorophenyl)-1-[(4-hydroxy-4-phenyl-1-piperidinyl)acetyl]urea; 1-(4-Hydroxy-4-phenylpiperidin-1-yl)-2-{[3-(4-chlorophenyl)ureido]}ethan-1-one; Urea, N-[4-chlorophenyl]-N'-[[(4-hydroxy-4-phenyl-1-piperidinyl)acetyl]amino]-; 70166-95-9; 3-(p-Chlorophenyl)-1-[(4-hydroxy-4-phenylpiperidino)acetyl]urea
EINECS	Contact for details

Quality Control

Our 3-(p-Chlorophenyl)-1-[(4-Hydroxy-4-Phenylpiperidino)Acetyl]Urea is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay (HPLC), related substances, and residual solvents. We support development and commercial projects with material suitable for research use through to cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.