Description

Phenylbutazonecalciumsalt is the calcium salt derivative of the non-steroidal anti-inflammatory drug (NSAID) phenylbutazone. This formulation offers enhanced stability and handling properties compared to the free acid, making it a valuable intermediate for pharmaceutical synthesis. It is primarily utilized by manufacturers in the veterinary and pharmaceutical industries for the development of anti-inflammatory and analgesic formulations. The compound's specific salt form can improve solubility and bioavailability profiles in final drug products.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of anti-inflammatory APIs (Active Pharmaceutical Ingredients).
• Veterinary Medicine Production: Used in the manufacture of injectable or oral formulations for treating pain and inflammation in large animals, particularly horses and livestock.
• Research & Development: Serves as a reference standard or chemical entity in pharmacological and pharmacokinetic studies within academic and industrial R&D labs.
• Analytical Standard: Employed as a high-purity standard for quality control testing (e.g., HPLC, LC-MS) in pharmaceutical manufacturing.
• Formulation Development: Explored in pre-formulation studies to develop novel drug delivery systems leveraging its calcium salt properties.

Basic Information

Product Name	Phenylbutazonecalciumsalt
CAS No.	70145-64-7
Molecular Formula	C38H34CaN4O6 (or commonly represented as (C19H20N2O2)2Ca)
Molecular Weight	698.79 g/mol
Synonyms	Phenylbutazone Calcium Salt; Calcium Phenylbutazone; 4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione Calcium Salt; Butazolidin Calcium; Phenylbutazone Ca Salt; 1,2-Diphenyl-4-butyl-3,5-pyrazolidinedione Calcium Salt; Phenylbutazoncalcium; EQ-601 Calcium Salt
EINECS	Contact for details

Quality Control

Our Phenylbutazonecalciumsalt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and impurity profiles, suitable for use as a pharmaceutical intermediate. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and heavy metals is provided with every shipment. We support compliance with cGMP and relevant pharmacopeial guidelines (e.g., USP, EP) for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (Calcium)	Positive
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.