Description

Methylfolate CAS NO 70114-87-3 is the biologically active form of folate, a critical cofactor in one-carbon metabolism. This high-purity compound is essential for industries requiring a direct and bioavailable source of folate that bypasses the enzymatic conversion needed by folic acid. It is primarily sought after by manufacturers in the pharmaceutical and nutraceutical sectors for formulating advanced dietary supplements and medical foods targeting specific metabolic pathways.

Application

• Pharmaceutical Formulations: Active pharmaceutical ingredient (API) in prescription medications for treating folate deficiency, particularly in individuals with MTHFR polymorphism.
• Dietary Supplements: Key ingredient in high-efficacy multivitamins, prenatal vitamins, and standalone folate supplements for enhanced bioavailability.
• Medical Nutrition: Component of specialized medical foods and clinical nutrition products designed for metabolic support.
• Research & Development: Standard and reagent for biochemical research, clinical studies, and in vitro diagnostic applications.
• Cosmeceuticals: Incorporated into advanced skincare formulations for its role in cellular repair and regeneration.

Basic Information

Product Name	Methylfolate
CAS No.	70114-87-3
Molecular Formula	C20H25N7O6
Molecular Weight	459.46 g/mol
Synonyms	(6S)-5-Methyltetrahydrofolic acid; (6S)-5-Methyltetrahydrofolate; L-Methylfolate; Metafolin®; Levomefolic acid; 5-MTHF; 5-Methyltetrahydrofolate; Quatrefolic®
EINECS	Contact for details

Quality Control

Our Methylfolate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and nutraceutical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/IR)	Conforms to standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Microbiological Control	Meets standard for dietary ingredients

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.