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Psychosine-3'-Sulfate Ester CAS NO 70005-46-8


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CAS No.:70005-46-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Psychosine-3'-Sulfate Ester is a specialized sulfated glycosphingolipid derivative, a key intermediate in the study of sphingolipid metabolism and lysosomal storage disorders. Its value lies in its role as a critical reference standard and research reagent for investigating enzymatic pathways, particularly those involving galactocerebrosidase and related sulfatases. This compound is essential for researchers and developers in the pharmaceutical, biotechnology, and diagnostic sectors focused on metabolic disease research, drug discovery, and the development of enzyme replacement therapies.

Application

  • Biochemical Research: Used as a high-purity substrate or inhibitor in enzymatic assays to study galactocerebrosidase and sulfatase activities.
  • Pharmaceutical Development: Serves as a critical reference standard in the research and development of therapies for lysosomal storage diseases like Krabbe disease and metachromatic leukodystrophy.
  • Diagnostic Reagents: Employed in the formulation of calibrators and controls for diagnostic kits targeting sphingolipid metabolism disorders.
  • Metabolic Pathway Analysis: A vital tool for in vitro and ex vivo studies to map and quantify metabolic fluxes in sphingolipid catabolism.
  • Academic Research: Fundamental reagent for university and institutional labs studying neurochemistry, cell signaling, and lipid biology.

Basic Information

Product Name Psychosine-3'-Sulfate Ester
CAS No. 70005-46-8
Molecular Formula C24H47NO9S
Molecular Weight 525.70 g/mol
Synonyms Galactosylsphingosine 3'-Sulfate; Psychosine Sulfate; D-Galactosyl-β1-1'-sphingosine 3'-Sulfate; 1-O-β-D-Galactopyranosyl-sphingosine 3'-Sulfate; Sulfated Psychosine; Lysogalactosylceramide Sulfate; (2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl β-D-galactopyranoside 3'-Sulfate
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Quality Control

Our Psychosine-3'-Sulfate Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, and our quality system supports traceability and documentation for regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC/MS) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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