Description

(1Ar,4E,10Ar)-1A,3,6,10A-Tetrahydro-1A,5,9-Trimethyloxireno[4,5]Cyclodeca[1,2-B]Furan-10(2H)-One CAS NO 7727-79-9 is a complex, high-purity sesquiterpene lactone derivative with a unique oxireno-fused cyclodecane structure. This compound matters as a sophisticated chemical intermediate and research standard for the synthesis of novel bioactive molecules and advanced materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical sectors.

Application

• Advanced Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Agrochemical Research: Used in the development of new-generation, biologically active compounds for crop protection and pest management.
• Fine Chemical Synthesis: Acts as a precursor for complex fragrance ingredients, specialty polymers, and other high-value chemical products.
• Academic & Industrial R&D: Employed as a reference standard and starting material in organic chemistry research to explore new reaction pathways and catalytic processes.
• Material Science: Investigated for its potential in creating novel organic frameworks and functional materials with specific optical or electronic properties.

Basic Information

Product Name	(1Ar,4E,10Ar)-1A,3,6,10A-Tetrahydro-1A,5,9-Trimethyloxireno[4,5]Cyclodeca[1,2-B]Furan-10(2H)-One
CAS No.	7727-79-9
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	Parthenolide; (-)-Parthenolide; Santamarin; 4,5-Epoxy-6,10-guaiadien-8-one; 1,10-Epoxy-4-guaien-6-one; Tanaparthin α-peroxide; 4,5α-Epoxy-6βH,7αH,10αH-guaia-1(5),11(13)-dien-12,8β-olide
EINECS	231-779-6

Quality Control

Our (1Ar,4E,10Ar)-1A,3,6,10A-Tetrahydro-1A,5,9-Trimethyloxireno[4,5]Cyclodeca[1,2-B]Furan-10(2H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.