Description

1,4-Bis-(2-Hydroxy-1-Phenyl-Ethyl)-Piperazine-2,5-Dione is a specialized piperazine dione derivative, a high-purity organic building block of significant interest in advanced chemical synthesis. Its molecular structure, featuring dual hydroxyphenyl arms, makes it a valuable precursor for creating complex heterocyclic compounds and functional materials. This compound is primarily sought by research institutions and industrial R&D departments in the pharmaceutical and fine chemical sectors for developing novel active ingredients and sophisticated ligands.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents and other bioactive molecules.
• Ligand Synthesis: Used in the preparation of complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Advanced Material Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with specific thermal or optical properties.
• Asymmetric Catalysis: Employed in the synthesis of chiral catalysts and auxiliaries for enantioselective reactions.
• Bioconjugation Chemistry: Its functional groups make it suitable for creating linkers in bioconjugation applications for drug delivery systems.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new reaction pathways and heterocyclic chemistry.

Basic Information

Product Name	1,4-Bis-(2-Hydroxy-1-Phenyl-Ethyl)-Piperazine-2,5-Dione
CAS No.	7592-99-6
Molecular Formula	C20H22N2O4
Molecular Weight	354.40 g/mol
Synonyms	1,4-Bis(2-hydroxy-1-phenylethyl)piperazine-2,5-dione; 1,4-Bis(2-hydroxy-2-phenylethyl)piperazine-2,5-dione; 2,5-Dioxo-1,4-bis(2-hydroxy-1-phenylethyl)piperazine; 1,4-Bis(1-hydroxy-2-phenylethyl)piperazine-2,5-dione; (2R,2'R,5S,5'S)-1,1'-(2,5-Dioxopiperazine-1,4-diyl)bis(2-phenylethane-2,1-diyl) diacetate (related ester); L-Phenylalanine derived piperazinedione dimer.
EINECS	Contact for details

Quality Control

Our 1,4-Bis-(2-Hydroxy-1-Phenyl-Ethyl)-Piperazine-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.