Description

Trinactin is a potent macrotetrolide antibiotic and ionophore, primarily recognized for its ability to transport potassium ions across biological membranes. This compound is of significant interest in biochemical and pharmacological research for studying ion transport mechanisms and membrane physiology. It serves as a critical research tool for scientists in the fields of microbiology, bioinorganic chemistry, and cellular biology, facilitating studies on antibiotic activity, membrane potential, and ion-selective transport.

Application

• Biochemical Research: Used as a potassium-specific ionophore to study ion transport across lipid bilayers and biological membranes.
• Microbiological Studies: Employed in research to investigate its antibiotic properties against Gram-positive bacteria and other microorganisms.
• Membrane Physiology: A key tool for modulating intracellular potassium levels and studying membrane potential in cells and organelles.
• Bioinorganic Chemistry: Utilized in research on cation selectivity and the mechanism of action of natural ionophores.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical and life science laboratories.

Basic Information

Product Name	Trinactin
CAS No.	7561-71-9
Molecular Formula	C₄₄H₇₂O₁₂
Molecular Weight	793.04 g/mol
Synonyms	Trinactin; Antibiotic A-5283; Macrotetrolide B; Nonactin Homolog; NSC 177375; 39,40,41,42,43,44,45,46-Octahydro-39,40,41,42,43,44,45,46-octahydroxy-5,14:6,13:7,12:8,11-tetrakis[1,2]dioxolano[4,5-f:4',5'-f']cycloocta[1,2-b:5,6-b']dipyran-2,9,16,23(5H,14H,6H,13H,7H,12H,8H,11H)-tetrone
EINECS	Contact for details

Quality Control

Our Trinactin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.