Description

(20R)-Cholest-5-Ene-3β,20-Diol 3-Acetate CAS NO 7429-99-4 is a high-purity sterol derivative, specifically an acetylated dihydroxycholesterol, that serves as a critical intermediate in advanced organic synthesis. Its defined stereochemistry and functional groups make it a valuable building block for pharmaceutical research and the development of complex bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise, high-quality intermediates for steroid-based drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel steroid-based therapeutics and hormone analogs.
• Biochemical Research: Used as a standard or precursor in metabolic pathway studies, enzyme inhibition assays, and receptor binding studies related to cholesterol metabolism.
• Fine Chemical Synthesis: Serves as a versatile starting material for the preparation of more complex steroidal compounds with modified biological activity.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Nutraceutical Research: Investigated as a potential intermediate for the development of advanced dietary supplements targeting lipid metabolism.

Basic Information

Product Name	(20R)-Cholest-5-Ene-3β,20-Diol 3-Acetate
CAS No.	7429-99-4
Molecular Formula	C₂₉H₄₈O₃
Molecular Weight	444.70 g/mol
Synonyms	(20R)-Cholest-5-ene-3β,20-diol 3-acetate; 20(R)-Hydroxycholesterol 3-acetate; 3β-Acetoxy-20(R)-hydroxycholest-5-ene; 20R-Hydroxycholesterol acetate; Cholest-5-ene-3β,20(R)-diol 3-acetate; 20(R)-Dihydroxycholesterol 3-monoacetate; 3β-Acetoxycholest-5-en-20(R)-ol
EINECS	Contact for details

Quality Control

Every batch of (20R)-Cholest-5-Ene-3β,20-Diol 3-Acetate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.