Description

2,5-Piperazinedione,1,4-Bis(Hydroxymethyl)-(6Ci,7Ci,8Ci,9Ci) is a functionalized diketopiperazine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and valuable building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly those containing piperazine or diketopiperazine cores.
• Peptidomimetic Research: Serves as a constrained scaffold in the design and synthesis of peptidomimetics to modulate biological activity and improve metabolic stability.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Polymer Science: Acts as a monomer or cross-linking agent for the synthesis of specialty polyamides and polymers with unique thermal and mechanical properties.
• Agrochemical Synthesis: Employed as an intermediate in the production of advanced crop protection agents and herbicides.
• Chemical Biology Probes: Utilized in the construction of molecular probes for studying enzyme mechanisms and protein-protein interactions.

Basic Information

Product Name	2,5-Piperazinedione,1,4-Bis(Hydroxymethyl)-(6Ci,7Ci,8Ci,9Ci)
CAS No.	7383-56-4
Molecular Formula	C6H10N2O4
Molecular Weight	174.16 g/mol
Synonyms	1,4-Bis(hydroxymethyl)-2,5-piperazinedione; 2,5-Diketopiperazine-1,4-dimethanol; 1,4-Di(hydroxymethyl)-2,5-diketopiperazine; 1,4-Bis(hydroxymethyl)-2,5-diketopiperazine; 1,4-Dimethanol-2,5-piperazinedione; (3S,6S)-3,6-Bis(hydroxymethyl)piperazine-2,5-dione (for specific stereoisomer); Diketopiperazine dimethanol derivative
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione,1,4-Bis(Hydroxymethyl) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and other relevant techniques are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.