Description

Strychnine-n-Oxide CAS NO 7248-28-4 is a specific alkaloid derivative of strychnine, primarily utilized as a critical reference standard and intermediate in advanced chemical research and synthesis. This compound is essential for analytical and pharmacological studies, particularly in the investigation of metabolic pathways and the development of detection methodologies. It serves the needs of research institutions, pharmaceutical development laboratories, and forensic analysis facilities requiring high-purity, well-characterized chemical entities.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the qualitative and quantitative analysis of strychnine and its metabolites in complex matrices.
• Metabolic Pathway Research: Serves as a key intermediate or marker in studies investigating the biotransformation and detoxification pathways of strychnine alkaloids.
• Forensic Toxicology: Employed in the development and validation of analytical methods (e.g., LC-MS/MS, GC-MS) for the precise identification and quantification of strychnine-related compounds in forensic samples.
• Biochemical Research: Acts as a tool compound in enzymatic studies and receptor binding assays to understand specific biochemical interactions.
• Chemical Synthesis Intermediate: Utilized as a building block or precursor in the organic synthesis of more complex molecules for research purposes.
• Quality Control & Method Development: Essential for calibrating equipment and validating analytical procedures in quality control laboratories within the pharmaceutical and chemical industries.

Basic Information

Product Name	Strychnine-n-Oxide
CAS No.	7248-28-4
Molecular Formula	C21H22N2O2
Molecular Weight	334.42 g/mol
Synonyms	Strychnine N-Oxide; Strychnine Oxide; Strychnidin-10-one 1-Oxide; 10,11-Dimethoxy-4-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(17),2,4,6,13,15-hexaen-5-one 4-Oxide; Brucine N-Oxide (related compound); Strychnine 1-Oxide
EINECS	Contact for details

Quality Control

Our Strychnine-n-Oxide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure it meets the exacting standards required for research and reference applications. A detailed Certificate of Analysis (COA) is provided, documenting identity, purity, and analytical results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.