Description

(2-Hydroxyethyl)Triphenylphosphonium Bromide is a versatile organophosphorus salt widely used as a key reagent in organic synthesis. Its primary value lies in its role as a stable phosphonium ylide precursor for the Wittig reaction, enabling the efficient synthesis of alkenes from carbonyl compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and advanced materials.

Application

• Wittig Olefination Reagent: A crucial precursor for generating stabilized ylides to synthesize α,β-unsaturated esters, nitriles, and ketones.
• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) requiring specific alkene geometries.
• Agrochemical Synthesis: Employed in creating advanced crop protection agents and pesticide intermediates.
• Material Science: Acts as a building block for functionalized polymers, liquid crystals, and organic electronic materials.
• Catalysis & Ligand Preparation: Serves as a starting material for synthesizing phosphine ligands used in transition metal catalysis.
• Academic & R&D Laboratories: A fundamental reagent for methodological development and novel compound library synthesis in organic chemistry.

Basic Information

Product Name	(2-Hydroxyethyl)Triphenylphosphonium Bromide
CAS No.	7237-34-5
Molecular Formula	C20H20BrOP
Molecular Weight	387.25 g/mol
Synonyms	2-Hydroxyethyltriphenylphosphonium Bromide; (2-Hydroxyethyl)triphenylphosphonium Bromide; Ethanol, 2-(triphenylphosphonio)-, bromide; 2-(Triphenylphosphonio)ethanol Bromide; Hydroxyethyltriphenylphosphonium Bromide; NSC 154105; EINECS 230-632-1; Triphenyl(2-hydroxyethyl)phosphonium Bromide
EINECS	230-632-1

Quality Control

Our (2-Hydroxyethyl)Triphenylphosphonium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	192°C - 198°C
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.