Description

Monactin CAS NO 7182-54-9 is a member of the nonactin family of macrotetrolide antibiotics, known for its potent ionophoric properties. This compound is valued for its ability to form stable complexes with alkali metal cations, facilitating their transport across biological and artificial membranes. It is a critical research tool for scientists in biochemistry, pharmacology, and materials science, particularly for studies involving ion transport mechanisms, membrane biophysics, and as a model for synthetic ionophores.

Application

• Biochemical Research: Used as a specific potassium ionophore in studies of membrane transport, mitochondrial function, and cellular ion homeostasis.
• Pharmacological Studies: Serves as a reference compound for investigating the structure-activity relationships of macrotetrolide antibiotics and their effects on microbial and mammalian cells.
• Analytical Chemistry: Employed in ion-selective electrodes (ISEs) and sensors as a neutral carrier for potassium ion detection and measurement.
• Materials Science: Acts as a model compound for developing synthetic ion channels and advanced membrane materials for separation technologies.
• Antimicrobial Research: Studied for its baseline antibiotic activity against Gram-positive bacteria and fungi, providing insights for novel antibiotic development.

Basic Information

Product Name	Monactin
CAS No.	7182-54-9
Molecular Formula	C32H56O12
Molecular Weight	632.79 g/mol
Synonyms	Monactin; NSC 177382; Antibiotic X-464; Nonactin Homolog; Macrotetrolide A; (3R,6R,9S,12R,15S,18R,21S,24R)-3,6,9,12,15,18,21,24-Octamethyl-1,4,7,10,13,16,19,22-octaoxacyclotetracosan-2,5,8,11,14,17,20,23-octone
EINECS	Contact for details

Quality Control

Our Monactin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.