Description

[(2S,3S)-3-Hydroxy-8-Methyl-8-Azabicyclo[3.2.1]Oct-2-Yl]Methyl Benzoat E is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. Its defined stereochemistry and functional groups make it a critical building block for the development of active pharmaceutical ingredients (APIs) with specific biological activity. This compound is essential for research and production in the pharmaceutical and fine chemical industries, particularly for creating complex molecules with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of tropane alkaloid derivatives and other complex therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a crucial precursor in the research and scale-up of new drug candidates, especially those targeting the central nervous system.
• Asymmetric Synthesis: Utilized in stereoselective chemical reactions to construct molecules with specific three-dimensional configurations.
• Medicinal Chemistry Research: Used in academic and industrial R&D for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals requiring precise stereochemical control.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	[(2S,3S)-3-Hydroxy-8-Methyl-8-Azabicyclo[3.2.1]Oct-2-Yl]Methyl Benzoat E
CAS No.	7148-14-3
Molecular Formula	C16H21NO3
Molecular Weight	275.34 g/mol
Synonyms	Benzoyl Ester of 3-Hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-2-ylmethanol; (2S,3S)-3-Hydroxy-8-methyl-8-azoniabicyclo[3.2.1]octan-2-ylmethyl benzoate; 8-Methyl-8-azabicyclo[3.2.1]octan-3-ol, 2-(hydroxymethyl)-, benzoate (ester), (1R,2R,3S,5S)-rel-; Tropine benzoate derivative; (1R,2R,3S,5S)-3-Hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester benzoate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [(2S,3S)-3-Hydroxy-8-Methyl-8-Azabicyclo[3.2.1]Oct-2-Yl]Methyl Benzoat E is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We can support development and registration by supplying data packages suitable for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.