Description

Salicin is a natural phenolic glucoside and a key biochemical precursor to salicylic acid, offering significant value as a high-purity botanical extract and pharmaceutical intermediate. Its primary commercial importance lies in providing a natural, plant-derived pathway for anti-inflammatory and analgesic applications. This compound is essential for manufacturers in the pharmaceutical, nutraceutical, and cosmetic industries seeking standardized botanical actives for research, development, and production.

Application

• Pharmaceutical Intermediate: Critical precursor in the semi-synthesis of salicylic acid and related analgesic/anti-inflammatory APIs.
• Nutraceutical Formulations: Used as a standardized botanical extract in dietary supplements targeting joint health and natural pain relief.
• Cosmetic & Skincare Actives: Incorporated into formulations for its soothing and anti-irritant properties.
• Biochemical Research: Serves as a reference standard and substrate in enzymatic studies and metabolic pathway research.
• Plant Extract Standardization: Acts as a marker compound for the quality control of willow bark (Salix spp.) extracts.
• Veterinary Pharmaceuticals: Used in formulations for animal health applications.

Basic Information

Product Name	Salicin
CAS No.	7088-55-4
Molecular Formula	C13H18O7
Molecular Weight	286.28 g/mol
Synonyms	Salicoside; 2-(Hydroxymethyl)phenyl-β-D-glucopyranoside; Saligenin β-D-glucopyranoside; D-(-)-Salicin; Saligenin-β-D-glucoside; (2-Hydroxymethyl)phenyl-β-D-glucopyranoside; NSC 407180; Willow Bark Extract (primary marker)
EINECS	230-436-1

Quality Control

Our Salicin is produced under a strict quality management system to ensure batch-to-batch consistency and reliability. We offer grades suitable for various applications, with specifications that can meet the requirements of pharmaceutical (USP/EP reference standards), nutraceutical, and research markets. Comprehensive testing includes identity, purity, and impurity profiling. A Certificate of Analysis (COA) documenting all critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	-62° to -67° (c=3 in water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.